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Scientists May Have Finally Found a Solution to Antibiotic Resistance May 12, 2017

Antibiotic-resistant superbugs may be the gravest threat to human health in the 21st century. After over-prescribing antibiotics for decades, multiple strains of bacteria are now immune to treatment. Millions of people are infected with these superbugs every year in the US, and tens of thousands die. And that’s just the beginning. We may be in the early stages of the post-antibiotic era, and if this trend isn’t reversed, superbugs may be killing more people than cancer does by the year 2050.

As you might expect, the scientific community has been desperately trying to find a solution to this crisis for some time. And fortunately, scientists have made some significant progress in recent years. In 2016 for instance, researchers from the Northeastern University in Boston, Massachusetts discovered Teixobactin, the first antibiotic to be found in nearly 30 years. And with that discovery, they figured out an entirely new avenue of research that could bring about many more antibiotics in the near future.

Of course, that doesn’t really solve the problem with antibiotic resistant superbugs when you think about it. It only serves to kick the can down the road. It’s entirely possible that any new antibiotic that is brought to market, will be thoroughly abused by the medical and agricultural communities. New resistant strains of bacteria will emerge, and we’ll be back to square one.

What we really need is a whole new approach to using antibiotics and treating bacterial infections. Preferably, something that bacteria can’t readily adapt to. Fortunately, a researcher by the name of Dr. Bruce Geller has come up with a new treatment method that might just fit the bill.

“Bacteria will develop resistance to any one antibiotic or antimicrobial given enough time,” says Dr. Bruce Geller, a professor of microbiology at Oregon State University. “Because they’ve had a 4 billion year head start in the evolution of mechanisms to adapt to changing environments, they’re very, very good at getting around any antimicrobial they might encounter.”

So rather than just coming up with a new antibiotic, which bacterial strains would surely become immune to, he’s developed a compound that when exposed to bacteria, eliminates their resistance to antibiotics.

Geller’s megaweapon is a PPMO designed to neutralize resistance mechanisms in bacteria, leaving them vulnerable to antibiotics. “This molecule can restore sensitivity to standard, already-approved antibiotics in bacteria that are now resistant to those antibiotics,” Geller says, which eliminates the need to invest time and money in developing new antibiotics. So how does this PPMO work?

A PPMO is a type of synthetic molecule that mimics DNA and can bind to the ribonucleic acid (RNA) of a cell. RNA takes the information stored in the DNA of a cell, translating it into proteins that carry out the various functions of that cell.

Imagine a gene as instructions, written in a letter. Normally, the RNA receives this letter and carries out the instructions, creating the appropriate proteins. The PPMO instead intercepts the letter along the way, replacing it with one that commands the RNA to do nothing. So Geller’s team can create a PPMO that binds to the gene that produces NDM-1 — an enzyme that neutralizes antibiotics — and silences it. Suddenly, the bacterium has no defense mechanism.

Of course, PPMOs aren’t a broad, perfect solution. For instance, Geller points out that a different kind of PPMO would have to be developed for each type of infection. So this method will be mainly used when a doctor knows exactly what is afflicting a patient. Despite that, what Dr. Geller has created is probably the best solution to antibiotic resistance that has been developed so far, and is the best hope we have to stem the tide of the superbugs.

Joshua Krause was born and raised in the Bay Area. He is a writer and researcher focused on principles of self-sufficiency and liberty at Ready Nutrition. You can follow Joshua’s work at our Facebook page or on his personal Twitter.

Joshua’s website is Strange Danger

This information has been made available by Ready Nutrition

Originally published May 12th, 2017
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These Are the Diseases That Will Run Rampant When the SHTF March 13, 2017

Most people like to think that if society collapsed, the most common cause of death would be at the hands of other people. They like to imagine that the apocalypse will be filled with action packed shootouts and marauding gangs of looters. Obviously there would be a lot of violence if society collapsed, but the truth of the matter is that violence would be a secondary concern.

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Mother Nature Has Plans of Her Own

This is evident if you only take a quick look throughout history. During the most tumultuous times in human history, it wasn’t violence that killed the most people, but disease and starvation. Even during war, when violence reached its apex, most of the soldiers didn’t die from violence, and that remained the case until the 20th century. During the American Civil War for instance, for every three soldiers who died on the battlefield, five died of disease.

It’s important to remember that if society were to collapse, it would be tantamount to traveling back in time to when modern amenities didn’t exist. And without those amenities, there are a ton of pathogens that can kill you. So before you blow your entire prepping budget on guns and body armor, consider some of the many unglorified ways that the collapse of society could cut you down.

These are the Seven Likely Causes of Death When the SHTF

1. Superbugs

The world was a hell of a scary place before the invention of antibiotic medications. Any nick or scratch could lead to an untreatable infection, and communicable diseases often ran rampant. Nowadays our antibiotics can treat these diseases, but just barely. As various strains of bacteria become immune to these treatments, we’re rapidly approaching a post-antibiotic world that looks an awful lot like the old world. If society collapses then these souped up diseases are going to be unleashed without any inhibitions. Tuberculosis, staph, typhoid, strep throat, MRSA, and E. Coli will become all too common.

2. Water-Related Illness

If society collapses, people are going to suddenly find themselves reliant on local water sources, and unfortunately those water sources are going to be contaminated. It’s often the case that natural ponds and stream are already unsafe to drink, but the same disaster that cuts off your tap is going to make that water even more dangerous.

Without running water, people will be forces to leave their waste in their immediate environment, where it will likely mingle with local water sources. This among other unsanitary conditions can cause a whole host of water-borne diseases including gastroenteritis, Hepatitis A, intestinal parasites, Diphtheria, cholera, typhoid, and even polio. Here are 9 common water-borne illnesses to prepare for in a disaster scenario.

3. Mosquitoes and Rats

It takes all the might of modern civilization just to keep certain pests in check. But when the garbage trucks stop showing up and the swimming pools turn green, you can bet that the rats and mosquitoes will proliferate like crazy. And they’ll be carrying diseases that are the stuff of nightmares. Rats will carry the hantavirus, leptospirosis, salmonellosis, and the plague; and in North America, mosquitoes will most likely be carrying dengue fever. Here are some tips to rat-proof your preparedness supply closet.

4. Cold Weather

A lot of people will be forced to go without adequate shelter after the collapse. So when winter arrives, you’re going to see a lot more weather related ailments. We’re all very familiar with flu season, but most people don’t realize that cold weather conditions can spawn numerous diseases, most of them respiratory related. Between the lack of sunlight, people crowding indoors, and the poor circulation caused by cold weather, there will be more cases of strep throat, pneumonia, croup, bronchiolitis, ear infections, and the stomach flu. To prepare for this, understand that hospitals and medical care may not be available (or too dangerous to get to). You may want to consider storing natural remedies, herbal poultices and tinctures to assist in these cold weather ailments.

5. Malnutrition

In a roundabout way, malnutrition would probably be the leading cause of disease after the SHTF. That’s because your diet is tightly linked to the quality of your immune system, so if you’re not getting enough calories, protein, vitamins or minerals, you’re more susceptible to every ailment under the sun. However, malnutrition is most associated with conditions like scurvy, rickets, pellagra, goiters, and beriberi.

6. Cadavers

The collapse of society would destroy every kind abundance that the modern world provides us, and in return, the only thing that would be in abundance are the dead. Dead bodies, especially the kind that were infected with disease to begin with, pose a serious health threat. Without a functioning society, and with bodies piling up faster than they can be buried or cremated, these cadavers would litter our towns and cities, and would most likely pose a serious threat to local water supplies.

7. Disease

Overshadowing many of these medical ailments will be disease. In fact, many believe that disease would be the real killer if the world fell apart and would dwarf the number of casualties caused by violence. Diseases are opportunists and tend to surface at a time the conditions are right for them to flourish. A long-term emergency would be just the right time, wouldn’t you say? These 10 diseases could become common medical emergencies. Make sure you have a well supplied medical closet and a sick room prepared for these issues.

There is a Silver Lining

As bleak as that sounds however, there is a silver lining. Prepping to prevent disease and infection is a lost less intimidating, and a lot more affordable than preparing to face-off against your fellow-man.

In fact, it’s as simple as stocking up on very general supplies that you should be accumulating anyway. Having plenty of food, toiletries, basic medical supplies, and water purification tools, will go a long way toward keeping you safe from the ravages of disease.

Resources:

The Prepper’s Blueprint: A Step-by-Step Preparedness Guide to Get Through Any Disaster

The One-Year Pantry, Layer by Layer

The Prepared Home: 50 Essential Items to Put in Your Ultimate Survival Medical Kit

52 Weeks to Preparedness: An Emergency Preparedness Plan For Surviving Virtually Any Disaster

The 4 Most Likely Ways You Can Die If the SHTF

Joshua Krause was born and raised in the Bay Area. He is a writer and researcher focused on principles of self-sufficiency and liberty at Ready Nutrition. You can follow Joshua’s work at our Facebook page or on his personal Twitter.

Joshua’s website is Strange Danger

This information has been made available by Ready Nutrition

Originally published March 13th, 2017
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